The Center for Digital Innovation (CDI-Negev) is non-profit innovation center, located in the Gav-Yam Negev Park in Beer-Sheba (Israel), the growing ‘Silicon Valley’ of the Middle East. We want to make the world a better place: a place where the individual stands at the center, supported by beneficial technologies that emerge out of visionary thinking, evidence-based research, top-notch engineering and strategic investment. With this paradigm shift, CDI aims to improve quality of life for individuals globally. CDI works in the areas of digital healthcare; social welfare, with a spotlight on healthy aging; education; and smart cities. In partnership with Ben-Gurion University of the Negev, we converge experienced entrepreneurs, start-up companies, innovators, researchers, industry leaders, academics, the public sector and investors to generate a new type of ROI – Return on Innovation. Together, we create opportunities to pioneer research, usher ideas to market and foster tangible and practical solutions to some of today’s and tomorrow’s main challenges.